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Extracellular vesicles from stem cells rescue cellular phenotypes and behavioral deficits in SHANK3-associated ASD neuronal and mouse models, Choudhary, A., Rosh, I., Hussein, Y., Netser, S., Shemen, A., Suliman, T., Rike, W. A., Simchi, L., Shklyar, B., Abu-Akel, A., Zinger, A., Offen, D., Wagner, S. & Stern, S., Dec 2026, In: Cell Death and Disease. 17, 1, 244.
Gene Editing Strategies for Neurological and Mental Disorders: Advances in Delivery, Methodology, and Clinical Translation, Elias, A. & Stern, S., Apr 2026, In: Cells. 15, 8, 720.
Brain extracellular matrix implications in multiple neurological disorders revealed through a meta-analysis of transcriptional changes, Sadis, H., Rike, W. A., Peles, D., Hussein, Y., Stern, T., Sagi, I. & Stern, S., Feb 2026, In: Neurobiology of Disease. 219, 107263.
Music enhances lipid nanoparticle brain delivery and mRNA transfection in brain cells, Mora-Raimundo, P., Gilon, A., Kadosh, H., Richtman, Y., Sela, M., Ackerman, S., Chen, G., Abel, R., Kagan, S., Sharf-Pauker, N., Gigi, O., Abumanhal-Masarweh, H., Tripathi, U., Saada, M., Shemen, A., Link-Sourani, D., Shklover, J., Farah, R., Horowitz-Kraus, T. & Hadjidemetriou, M. & 3 others, Kostarelos, K., Stern, S. & Schroeder, A., 10 Dec 2025, In: Journal of Controlled Release. 388, 114301.
Detecting suicide risk in bipolar disorder patients from lymphoblastoid cell lines genetic signatures, Sharma, O., Nayak, R., Mizrahi, L., Rike, W. A., Choudhary, A., Sadis, H., Hussein, Y., Rosh, I., Tripathi, U., Shemen, A., Stern, Y., Squassina, A., Alda, M. & Stern, S., Dec 2025, In: Translational Psychiatry. 15, 1, 339.
The effects of bipolar disorder granule cell hyperexcitability and lithium therapy on pattern separation in a computational model of the dentate gyrus, Singh, S., Khayachi, A., Stern, S., Trappenberg, T., Alda, M. & Nunes, A., Dec 2025, In: Translational Psychiatry. 15, 1, 385.
Prader-Willi syndrome: Genetics, clinical symptoms, and model systems, Saade, M., Rike, W. A., Sharma, O., Abu-Akel, A. & Stern, S., Nov 2025, In: Genomic Psychiatry. 1, 6, p. 17-37
XPRESSO: Rapid genetic engineering of human pluripotent stem cells for durable overexpression using a modular anti-silencing vector, Wexler, Y., Grinstein, H., Huber, I., Glatstein, S., Ghiringhelli, M., Edri, O., Landesberg, M., Shiff, D., Arbel, G., Rosh, I., Choudhary, A., Stern, S. & Gepstein, L., 14 Oct 2025, In: Stem Cell Reports. 20, 10, 102603.
Digestive Neurobiology in Autism: From Enteric and Central Nervous System Interactions to Shared Genetic Pathways, Robas, R., Tripathi, U., Rike, W. A., Sharma, O. & Stern, S., Oct 2025, In: International Journal of Molecular Sciences. 26, 19, 9580.
Molecular Signatures of Schizophrenia and Insights into Potential Biological Convergence, Saada, M. & Stern, S., Oct 2025, In: International Journal of Molecular Sciences. 26, 19, 9830.
From Genome-Wide SNPs to Neuroimmune Crosstalk: Mapping the Genetic Landscape of IBD and Its Brain Overlap, Tripathi, U., Stern, Y., Dagan, I., Nayak, R., Romanovsky, E., Zittan, E. & Stern, S., Oct 2025, In: Biology. 14, 10, 1433.
Extracellular Origins of Cognition: Lessons from Primate Neocortical ECM, Stern, S., Jul 2025, In: Proteomics. 25, 14, e13979.
Uncovering convergence and divergence between autism and schizophrenia using genomic tools and patients’ neurons, Romanovsky, E., Choudhary, A., Peles, D., Abu-Akel, A. & Stern, S., Mar 2025, In: Molecular Psychiatry. 30, 3, p. 1019-1028 10 p., 12.
TMEM16F regulates pathologic α-synuclein secretion and spread in cellular and mouse models of Parkinson's disease, Cohen-Adiv, S., Amer-Sarsour, F., Berdichevsky, Y., Boxer, E., Goldstein, O., Gana-Weisz, M., Tripathi, U., Rike, W. A., Prag, G., Gurevich, T., Giladi, N., Stern, S., Orr-Urtreger, A., Friedmann-Morvinski, D. & Ashkenazi, A., Feb 2025, In: Aging Cell. 24, 2, e14387.
The Impact of Electrophysiological Diversity on Pattern Completion in Lithium Nonresponsive Bipolar Disorder: A Computational Modeling Approach, Nunes, A., Singh, S., Khayachi, A., Stern, S., Trappenberg, T. & Alda, M., Jan 2025, In: Brain and Behavior. 15, 1, e70209.
Previously defined variants of uncertain significance may play an important role in epilepsy and interactions between certain variants may become pathogenic, Hussein, Y., Weisblum-Neuman, H., Ben Zeev, B. & Stern, S., Dec 2024, In: Epilepsia Open. 9, 6, p. 2443-2453 11 p.
Upregulated ECM genes and increased synaptic activity in Parkinson’s human DA neurons with PINK1/ PRKN mutations, Tripathi, U., Rosh, I., Ben Ezer, R., Nayak, R., Hussein, Y., Choudhary, A., Djamus, J., Manole, A., Houlden, H., Gage, F. H. & Stern, S., Dec 2024, In: npj Parkinson's Disease. 10, 1, 103.
Synaptic dysfunction and extracellular matrix dysregulation in dopaminergic neurons from sporadic and E326K-GBA1 Parkinson’s disease patients, Rosh, I., Tripathi, U., Hussein, Y., Rike, W. A., Djamus, J., Shklyar, B., Manole, A., Houlden, H., Winkler, J., Gage, F. H. & Stern, S., Dec 2024, In: npj Parkinson's Disease. 10, 1, 38.
NMDA Receptors in Neurodevelopmental Disorders: Pathophysiology and Disease Models, Tumdam, R., Hussein, Y., Garin-Shkolnik, T. & Stern, S., Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12366.
Current progress in understanding schizophrenia using genomics and pluripotent stem cells: A meta-analytical overview, Choudhary, A., Peles, D., Nayak, R., Mizrahi, L. & Stern, S., Nov 2024, In: Schizophrenia Research. 273, p. 24-38 15 p.
Shank3 mutation impairs glutamate signaling and myelination in ASD mouse model and human iPSC-derived OPCs, Fischer, I., Shohat, S., Leichtmann-Bardoogo, Y., Nayak, R., Wiener, G., Rosh, I., Shemen, A., Tripathi, U., Rokach, M., Bar, E., Hussein, Y., Castro, A. C., Chen, G., Soffer, A., Schokoroy-Trangle, S., Elad-Sfadia, G., Assaf, Y., Schroeder, A., Monteiro, P. & Stern, S. & 2 others, Maoz, B. M. & Barak, B., 11 Oct 2024, In: Science Advances. 10, 41, eadl4573.
Monozygotic twins discordant for schizophrenia differ in maturation and synaptic transmission, Stern, S., Zhang, L., Wang, M., Wright, R., Rosh, I., Hussein, Y., Stern, T., Choudhary, A., Tripathi, U., Reed, P., Sadis, H., Nayak, R., Shemen, A., Agarwal, K., Cordeiro, D., Peles, D., Hang, Y., Mendes, A. P. D., Baul, T. D. & Roth, J. G. & 9 others, Coorapati, S., Boks, M. P., McCombie, W. R., Hulshoff Pol, H., Brennand, K. J., Réthelyi, J. M., Kahn, R. S., Marchetto, M. C. & Gage, F. H., Oct 2024, In: Molecular Psychiatry. 29, 10, p. 3208-3222 15 p.
Case Report: A Case of a Patient with Smith–Magenis Syndrome and Early-Onset Parkinson’s Disease, Stern, T., Hussein, Y., Cordeiro, D., Sadis, H., Garin-Shkolnik, T., Spiegel, R., Cohen, S., Harari, R., Schlesinger, I. & Stern, S., Aug 2024, In: International Journal of Molecular Sciences. 25, 15, 8447.
Focusing on the tetra-partite synapse in Parkinson s disease research using human patient-derived neurons, Cordeiro, D., Stern, T. & Stern, S., May 2024, In: Neural Regeneration Research. 19, 5, p. 979-981 3 p.
Altered Expression of PDE4 Genes in Schizophrenia: Insights from a Brain and Blood Sample Meta-Analysis and iPSC-Derived Neurons, Burrack, N., Yitzhaky, A., Mizrahi, L., Wang, M., Stern, S. & Hertzberg, L., May 2024, In: Genes. 15, 5, 609.
A pilot study examining the impact of lithium treatment and responsiveness on mnemonic discrimination in bipolar disorder, Madanlal, D., Guinard, C., Nuñez, V. P., Becker, S., Garnham, J., Khayachi, A., Léger, S., O'Donovan, C., Singh, S., Stern, S., Slaney, C., Trappenberg, T., Alda, M. & Nunes, A., 15 Apr 2024, In: Journal of Affective Disorders. 351, p. 49-57 9 p.
Tyro3 promotes the maturation of glutamatergic synapses, Miao, S., Fourgeaud, L., Burrola, P. G., Stern, S., Zhang, Y., Happonen, K. E., Novak, S. W., Gage, F. H. & Lemke, G., 2024, In: Frontiers in Neuroscience. 18, 1327423.
NGLY1 mutations cause protein aggregation in human neurons, Manole, A., Wong, T., Rhee, A., Novak, S., Chin, S. M., Tsimring, K., Paucar, A., Williams, A., Newmeyer, T. F., Schafer, S. T., Rosh, I., Kaushik, S., Hoffman, R., Chen, S., Wang, G., Snyder, M., Cuervo, A. M., Andrade, L., Manor, U. & Lee, K. & 4 others, Jones, J. R., Stern, S., Marchetto, M. C. & Gage, F. H., 26 Dec 2023, In: Cell Reports. 42, 12, 113466.
Brain-Targeted Liposomes Loaded with Monoclonal Antibodies Reduce Alpha-Synuclein Aggregation and Improve Behavioral Symptoms in Parkinson's Disease, Sela, M., Poley, M., Mora-Raimundo, P., Kagan, S., Avital, A., Kaduri, M., Chen, G., Adir, O., Rozencweig, A., Weiss, Y., Sade, O., Leichtmann-Bardoogo, Y., Simchi, L., Aga-Mizrachi, S., Bell, B., Yeretz-Peretz, Y., Or, A. Z., Choudhary, A., Rosh, I. & Cordeiro, D. & 16 others, Cohen-Adiv, S., Berdichevsky, Y., Odeh, A., Shklover, J., Shainsky-Roitman, J., Schroeder, J. E., Hershkovitz, D., Hasson, P., Ashkenazi, A., Stern, S., Laviv, T., Ben-Zvi, A., Avital, A., Ashery, U., Maoz, B. M. & Schroeder, A., 21 Dec 2023, In: Advanced Materials. 35, 51, 2304654.
Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations, Hussein, Y., Tripathi, U., Choudhary, A., Nayak, R., Peles, D., Rosh, I., Rabinski, T., Djamus, J., Vatine, G. D., Spiegel, R., Garin-Shkolnik, T. & Stern, S., Dec 2023, In: Translational Psychiatry. 13, 1, 246.
Immunoglobulin genes expressed in lymphoblastoid cell lines discern and predict lithium response in bipolar disorder patients, Mizrahi, L., Choudhary, A., Ofer, P., Goldberg, G., Milanesi, E., Kelsoe, J. R., Gurwitz, D., Alda, M., Gage, F. H. & Stern, S., Oct 2023, In: Molecular Psychiatry. 28, 10, p. 4280-4293 14 p.
The NO Answer for Autism Spectrum Disorder, Tripathi, M. K., Ojha, S. K., Kartawy, M., Hamoudi, W., Choudhary, A., Stern, S., Aran, A. & Amal, H., 4 Aug 2023, In: Advanced Science. 10, 22, 2205783.
Proteins and Transcriptional Dysregulation of the Brain Extracellular Matrix in Parkinson’s Disease: A Systematic Review, Rike, W. A. & Stern, S., Apr 2023, In: International Journal of Molecular Sciences. 24, 8, 7435.
Information theory characteristics improve the prediction of lithium response in bipolar disorder patients using a support vector machine classifier, Tripathi, U., Mizrahi, L., Alda, M., Falkovich, G. & Stern, S., Mar 2023, In: Bipolar Disorders. 25, 2, p. 110-127 18 p.
Intrinsic Excitability in Layer IV–VI Anterior Insula to Basolateral Amygdala Projection Neurons Correlates with the Confidence of Taste Valence Encoding, Chandran, S. K., Yiannakas, A., Kayyal, H., Salalha, R., Cruciani, F., Mizrahi, L., Khamaisy, M., Stern, S. & Rosenblum, K., Jan 2023, In: eNeuro. 10, 1, ENEURO.0302-22.2022.
Editorial: Advances in neural reprogramming, disease modeling and therapeutic insights, Lau, S. & Stern, S., 2023, In: Frontiers in Aging Neuroscience. 15, 1259765.
Druggable transcriptomic pathways revealed in Parkinson’s patient-derived midbrain neurons, van den Hurk, M., Lau, S., Marchetto, M. C., Mertens, J., Stern, S., Corti, O., Brice, A., Winner, B., Winkler, J., Gage, F. H. & Bardy, C., Dec 2022, In: npj Parkinson's Disease. 8, 1, 134.
Reduced synaptic activity and dysregulated extracellular matrix pathways in midbrain neurons from Parkinson’s disease patients, Stern, S., Lau, S., Manole, A., Rosh, I., Percia, M. M., Ben Ezer, R., Shokhirev, M. N., Qiu, F., Schafer, S., Mansour, A. A. F., Mangan, K. P., Stern, T., Ofer, P., Stern, Y., Diniz Mendes, A. P., Djamus, J., Moore, L. R., Nayak, R., Laufer, S. H. & Aicher, A. & 13 others, Rhee, A., Wong, T. L., Nguyen, T., Linker, S. B., Winner, B., Freitas, B. C., Jones, E., Sagi, I., Bardy, C., Brice, A., Winkler, J., Marchetto, M. C. & Gage, F. H., Dec 2022, In: npj Parkinson's Disease. 8, 1, 103.
Generation and characterization of iPSC lines (UOHi003-A, UOHi002-A) from a patient with SHANK3 mutation and her healthy mother, Nayak, R., Rosh, I., Rabinski, T., Falik, D., Mendel Percia, M. & Stern, S., Oct 2022, In: Stem Cell Research. 64, 102899.
Intrinsic excitability in layer IV-VI anterior insula to basolateral amygdala projection neurons encodes the confidence of taste valence, Chandran, S. K., Yiannakas, A., Kayyal, H., Salalha, R., Cruciani, F., Mizrahi, L., Khamaisy, M., Stern, S. & Rosenblum, K., 23 May 2022, In: bioRxiv.
Neonatal neuronal WWOX gene therapy rescues Wwox null phenotypes, Repudi, S., Kustanovich, I., Abu-Swai, S., Stern, S. & Aqeilan, R. I., 7 Dec 2021, In: EMBO Molecular Medicine. 13, 12, e14599.
IQSEC2 mutation associated with epilepsy, intellectual disability, and autism results in hyperexcitability of patient-derived neurons and deficient synaptic transmission, Brant, B., Stern, T., Shekhidem, H. A., Mizrahi, L., Rosh, I., Stern, Y., Ofer, P., Asleh, A., Umanah, G. K. E., Jada, R., Levy, N. S., Levy, A. P. & Stern, S., Dec 2021, In: Molecular Psychiatry. 26, 12, p. 7498-7508 11 p.
Age-dependent instability of mature neuronal fate in induced neurons from Alzheimer's patients, Mertens, J., Herdy, J. R., Traxler, L., Schafer, S. T., Schlachetzki, J. C. M., Böhnke, L., Reid, D. A., Lee, H., Zangwill, D., Fernandes, D. P., Agarwal, R. K., Lucciola, R., Zhou-Yang, L., Karbacher, L., Edenhofer, F., Stern, S., Horvath, S., Paquola, A. C. M., Glass, C. K. & Yuan, S. H. & 5 others, Ku, M., Szücs, A., Goldstein, L. S. B., Galasko, D. & Gage, F. H., 2 Sep 2021, In: Cell Stem Cell. 28, 9, p. 1533-1548.e6
Mood stabilizers in psychiatric disorders and mechanisms learnt from in vitro model systems, Nayak, R., Rosh, I., Kustanovich, I. & Stern, S., 1 Sep 2021, In: International Journal of Molecular Sciences. 22, 17, 9315.
Modeling genetic epileptic encephalopathies using brain organoids, Steinberg, D. J., Repudi, S., Saleem, A., Kustanovich, I., Viukov, S., Abudiab, B., Banne, E., Mahajnah, M., Hanna, J. H., Stern, S., Carlen, P. L. & Aqeilan, R. I., 9 Aug 2021, In: EMBO Molecular Medicine. 13, 8, e13610.
Deficient LEF1 expression is associated with lithium resistance and hyperexcitability in neurons derived from bipolar disorder patients, Santos, R., Linker, S. B., Stern, S., Mendes, A. P. D., Shokhirev, M. N., Erikson, G., Randolph-Moore, L., Racha, V., Kim, Y., Kelsoe, J. R., Bang, A. G., Alda, M., Marchetto, M. C. & Gage, F. H., Jun 2021, In: Molecular Psychiatry. 26, 6, p. 2440-2456 17 p.
An epilepsy-associated KCNT1 mutation enhances excitability of human iPSC-derived neurons by increasing slack KNa currents, Quraishi, I. H., Stern, S., Mangan, K. P., Zhang, Y., Ali, S. R., Mercier, M. R., Marchetto, M. C., McLachlan, M. J., Jones, E. M., Gage, F. H. & Kaczmarek, L. K., 2019, In: Journal of Neuroscience. 39, 37, p. 7438-7449 12 p.
Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients' responsiveness to lithium, Stern, S., Santos, R., Marchetto, M. C., Mendes, A. P. D., Rouleau, G. A., Biesmans, S., Wang, Q. W., Yao, J., Charnay, P., Bang, A. G., Alda, M. & Gage, F. H., 1 Jun 2018, In: Molecular Psychiatry. 23, 6, p. 1453-1465 13 p.
Involvement of Potassium and Cation Channels in Hippocampal Abnormalities of Embryonic Ts65Dn and Tc1 Trisomic Mice, Stern, S., Segal, M. & Moses, E., 1 Sep 2015, In: eBioMedicine. 2, 9, p. 1048-1062 15 p.
Design of logical devices with neuronal cultures, Stern, S., 2012, Control motor y cognicion, propiedades emergentes de redes neuronales. Romo, R. (ed.). Mexico: El Colegio Nacional

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